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diabetes type 2 natural way ketosis (☑ etiology) | diabetes type 2 natural way onsethow to diabetes type 2 natural way for Diabetic neuropathy refers to various types of nerve damage associated with diabetes mellitus. Symptoms depend on the site of nerve damage and can include motor changes such as weakness; sensory symptoms such as numbness, tingling, or pain; or autonomic changes such as urinary symptoms. These changes are thought to result from microvascular injury involving small blood vessels that supply nerves (vasa nervorum). Relatively common conditions which may be associated with diabetic neuropathy include distal symmetric polyneuropathy; third, fourth, or sixth cranial nerve palsy[1]; mononeuropathy; mononeuropathy multiplex; diabetic amyotrophy; and autonomic neuropathy.

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Signs and symptomsdiabetes type 2 natural way common complications (👍 youngest age in pediatrics) | diabetes type 2 natural way youngest age in pediatricshow to diabetes type 2 natural way for [edit][edit]

Illustration depicting areas affected by diabetic neuropathy

Diabetic neuropathy can affect any peripheral nerves including sensory neurons, motor neurons, and the autonomic nervous system. Therefore, diabetic neuropathy has the potential to affect essentially any organ system and can cause a range of symptoms. There are several distinct syndromes based on the organ systems affected.

Sensorimotor polyneuropathy[edit the 1 last update 03 Aug 2020 ]]

Longer nerve fibers are affected to a greater degree than shorter ones because nerve conduction velocity is slowed in proportion to a nerve''t follow a specific pattern, also called ""

  • Nerve damage from entrapment (e.g. median, ulnar, peroneal)
  • Symmetrical neuropathies:
    • Sensory
    • Autonomic
    • Distal symmetrical polyneuropathy (DSPN), the diabetic type of which is also known as diabetic peripheral neuropathy (DPN) (most common presentation)
  • Prevention[edit]

    This section needs expansion. You can help by adding to it. (March the 1 last update 03 Aug 2020 2017March 2017)

    Diabetic neuropathy can be largely prevented by maintaining blood glucose levels and lifestyle modifications.[8] Enhanced glucose control methods include more frequent subcutaneous insulin administration, continuous insulin infusion, oral antidiabetic agents, while lifestyle modifications may include exercise alone, or in combination with dietary modifications. Enhanced glucose control prevents the development of clinical neuropathy and reduces nerve abnormalities in type 1 diabetes, and delays the onset of neuropathy in both types of diabetes. However, such methods may increase the likelihood of experiencing a hypoglycemic event, and many of these more aggressive methods require more frequent insulin use which has been associated with excessive risk of falls.[9]

    the 1 last update 03 Aug 2020 TreatmentTreatment[edit][edit]

    Blood glucose management[edit][edit]

    Treatment of early manifestations of sensorimotor polyneuropathy involves improving glycemic control.[10] Tight control of blood glucose can reverse the changes of diabetic neuropathy if the neuropathy and diabetes are recent in onset. This is the primary treatment of diabetic neuropathy that may change the course of the condition as the other treatments focus on reducing pain and other symptoms.

    Topical agents[edit]

    Capsaicin applied to the skin in a 0.075% concentration has not been found to be more effective than placebo for treating pain associated with diabetic neuropathy. There is insufficient evidence to draw conclusions for more concentrated forms of capsaicin, clonidine, or lidocaine applied to the skin.[11] About 10% of people who use capsaicin cream have a large benefit.[12]

    Medicationsdiabetes type 2 natural way name (☑ vitamin d) | diabetes type 2 natural way natural medicationshow to diabetes type 2 natural way for [edit][edit]

    Medication options for pain control include antiepileptic drugs (AEDs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs).[13] Medication options for pain control include antiepileptic drugs (AEDs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs).[13]

    A systematic review concluded that ""/wiki/Tricyclic_antidepressants""mw-redirect""Tricyclic antidepressants""/wiki/Anticonvulsants""mw-redirect""Anticonvulsants""[14] A further analysis of previous studies showed that the agents carbamazepine, venlafaxine, duloxetine, and amitriptyline were more effective than placebo, but that comparative effectiveness between each agent is unclear.[15]

    The only three medications approved by the United States''s range of motion.[22] General muscle strengthening exercises will help to maintain muscle strength and reduce muscle wasting.[23] Aerobic exercise such as swimming and using a stationary bicycle can help peripheral neuropathy, but activities that place excessive pressure on the feet (e.g. walking long distances, running) may be contraindicated.[24]

    Heat, therapeutic ultrasound,[20] hot wax[20] are also useful for treating diabetic neuropathy.[20] Pelvic floor muscle exercises can improve sexual dysfunction caused by neuropathy.

    Other[editdiabetes type 2 natural way untreated (🔥 virus) | diabetes type 2 natural way testhow to diabetes type 2 natural way for ]

    Low-quality evidence supports a moderate-large beneficial effect of botulinum toxin injections.[11] There is insufficient evidence to draw firm conclusions for the utility of the cannabinoids nabilone and nabiximols.[11]

    Prognosis[edit the 1 last update 03 Aug 2020 ]]

    The mechanisms of diabetic neuropathy are poorly understood. At present, treatment alleviates pain and can control some associated symptoms, but the process is generally progressive.

    As a complication, there is an increased risk of injury to the feet because of loss of sensation (see diabetic foot). Small infections can progress to ulceration and this may require amputation.[25]

    Epidemiology[edit]

    diabetes type 2 natural way questionnaire (⭐️ food choices) | diabetes type 2 natural way uncontrolledhow to diabetes type 2 natural way for Globally diabetic neuropathy affects approximately 132 million people as of 2010 (1.9% of the population).[26]

    Diabetes is the the 1 last update 03 Aug 2020 leading known cause of neuropathy in developed countries, and neuropathy is the most common complication and greatest source of morbidity and mortality in diabetes. It is estimated that neuropathy affects 25% of people with diabetes.[27] Diabetic neuropathy is implicated in 50–75% of nontraumatic amputations. Diabetes is the leading known cause of neuropathy in developed countries, and neuropathy is the most common complication and greatest source of morbidity and mortality in diabetes. It is estimated that neuropathy affects 25% of people with diabetes.[27] Diabetic neuropathy is implicated in 50–75% of nontraumatic amputations.

    The main risk factor for diabetic neuropathy is hyperglycemia. In the DCCT (Diabetes Control and Complications Trial, 1995) study, the annual incidence of neuropathy was 2% per year but dropped to 0.56% with intensive treatment of Type 1 diabetics. The progression of neuropathy is dependent on the degree of glycemic control in both Type 1 and Type 2 diabetes. Duration of diabetes, age, cigarette smoking, hypertension, height, and hyperlipidemia are also risk factors for diabetic neuropathy.

    diabetes type 2 natural way keto (☑ with hyperglycemia) | diabetes type 2 natural way glucose rangehow to diabetes type 2 natural way for References[editdiabetes type 2 natural way normal range chart (⭐️ definition) | diabetes type 2 natural way vbidhow to diabetes type 2 natural way for ]

    1. ^ "". aao.org. 1 September 2017. Archived from the original on 22 December 2017.
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    3. ^^ Forbes, JM; Coughlan MT; Cooper ME (June 2008). "". Diabetes. 57 (6): 1446–1454. doi:10.2337/db08-0057. PMID 18511445. Archived from the original on 2009-04-15.
    4. ^ Javed S, Petropoulos IN, Alam U, Malik RA (Jan 2015). "". Ther Adv Chronic Dis. 6 (1): 15–28. doi:10.1177/2040622314552071. PMC 4269610. PMID 25553239.
    5. ^ Kanji JN, Anglin RE, Hunt DL, Panju A (April 2010). "". JAMA. 303 (15): 1526–32. doi:10.1001/jama.2010.428. PMID 20407062.
    6. ^ a b King SA (October 1, 2008). "". Consultant. 48 (11).
    7. ^ diabetes type 2 natural way fruit (☑ bedtime snacks) | diabetes type 2 natural way beta cellshow to diabetes type 2 natural way for Aristidis Veves; John M. Giurini; Frank W. LoGerfo (2012-06-12). The Diabetic Foot: Medical and Surgical Management (3rd ed.). Springer Science & Business Media. p. 34. ISBN 978-1-61779-791-0.
    8. ^ Pop-Busui, Rodica; Boulton, Andrew J.M.; Feldman, Eva L.; Bril, Vera; Freeman, Roy; Malik, Rayaz A.; Sosenko, Jay M.; Ziegler, Dan (20 December 2016). "". Diabetes Care. 40 (1): 136–154. doi:10.2337/dc16-2042. PMID 27999003. the 1 last update 03 Aug 2020
    9. ^ Callaghan, BC; Little, AA; Feldman, EL; Hughes, RAC (2012). "". Cochrane Database of Systematic Reviews (6). doi:10.1002/14651858.cd007543.pub2. PMC 4048127. Retrieved 15 March 2020.Callaghan, BC; Little, AA; Feldman, EL; Hughes, RAC (2012). "". Cochrane Database of Systematic Reviews (6). doi:10.1002/14651858.cd007543.pub2. PMC 4048127. Retrieved 15 March 2020.
    10. ^ The Diabetes Control and Complications Trial Research Group. (1995). "". Ann. Intern. Med. 122 (8): 561–8. doi:10.7326/0003-4819-122-8-199504150-00001. PMID 7887548.
    11. ^ a b c d e f g h i j k l m n Waldfogel, JM; Nesbit, SA; Dy, SM; Sharma, R; Zhang, A; Wilson, LM; Bennett, WL; Yeh, HC; Chelladurai, Y; Feldman, D; Robinson, KA (May 2017). "". Neurology (Systematic Review & Meta-Analysis). 88 (20): 1958–67. doi:10.1212/WNL.0000000000003882. PMID 28341643.
    12. ^ Derry, S; Rice, AS; Cole, P; Tan, T; Moore, RA (13 January 2017). "" (PDF). The Cochrane Database of Systematic Reviews (Systematic Review). 1: CD007393. doi:10.1002/14651858.CD007393.pub4. hdl:10044/1/49554. PMC 6464756. PMID 28085183.
    13. ^ a b Griebeler, ML; Morey-Vargas, OL; Brito, JP; Tsapas, A; Wang, Z; Carranza Leon, BG; Phung, OJ; Montori, VM; Murad, MH (November 2014). "". Annals of Internal Medicine (Systematic Review & Meta-Analysis). 161 (9): 639–49. doi:10.7326/M14-0511. PMID 25364885.
    14. diabetes type 2 natural way diet plan examples (🔴 genetic) | diabetes type 2 natural way bracelethow to diabetes type 2 natural way for ^ Wong MC, Chung JW, Wong TK (2007). "". BMJ. 335 (7610): 87. doi:10.1136/bmj.39213.565972.AE. PMC diabetes type 2 natural way virus (🔥 neuropathy treatment) | diabetes type 2 natural way yeast infectionshow to diabetes type 2 natural way for 1914460. PMID 17562735.
    15. ^ Griebeler ML, Morey-Vargas OL, Brito JP, Tsapas A, Wang Z, Carranza Leon BG, Phung OJ, Montori VM, Murad MH (4 Nov 2014). "". Ann Intern Med. 161 (9): 639–49. doi:10.7326/M14-0511. PMID 25364885.
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    17. diabetes type 2 natural way pathophys (👍 treat) | diabetes type 2 natural way how do you get ithow to diabetes type 2 natural way for ^ "" (PDF). Archived (PDF) from the original on 2016-02-08diabetes type 2 natural way treatment side effect (🔥 blood test) | diabetes type 2 natural way rashhow to diabetes type 2 natural way for . Retrieved 2013-01-26.
    18. ^ a b c d Ziegler, D; Fonseca, V (January–February 2015). "". Journal of Diabetes and Its Complications (Review). 29 (1): 146–56. doi:10.1016/j.jdiacomp.2014.08.008. PMID 25239450.
    19. ^ Wiffen, PJ; Derry, S; Bell, RF; Rice, AS; Tölle, TR; Phillips, T; Moore, RA (June 2017). "". Cochrane Database of Systematic Reviews (Systematic Review & Meta-Analysis). 6: CD007938. doi:10.1002/14651858.CD007938.pub4. PMC 6452908. PMID 28597471.
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    23. ^ diabetes type 2 natural way uncontrolled icd 10 (🔥 glut4) | diabetes type 2 natural way age of onsethow to diabetes type 2 natural way for Borges, Cristiane; Castao, Karine; Souto, Patricia; Zan, Tatiane; Pompeu, Jose; Fukuda, Thiago (2009). "" (PDF). The Journal of Applied Research. 9 (4): 147–158. Archived (PDF) from the original on 2012-03-23. Retrieved 2011-05-03.
    24. ^ diabetes type 2 natural way odor (👍 young age) | diabetes type 2 natural way insulin dependenthow to diabetes type 2 natural way for Typpo, Omaha (2010-12-26). "". Demand Media Inc. Archived from the original for 1 last update 03 Aug 2020 on 2012-03-13. Retrieved 2011-05-03.Typpo, Omaha (2010-12-26). "". Demand Media Inc. Archived from the original on 2012-03-13. Retrieved 2011-05-03.
    25. diabetes type 2 natural way need insulin (☑ occurs when) | diabetes type 2 natural way vs 1how to diabetes type 2 natural way for ^ Arad Y, Fonseca V, Peters A, Vinik A (2011). "". Diabetes Care. 34 (4): 1041–6. doi:10.2337/dc10-1666. PMC 3064020. PMID 21447666.
    26. ^ Vos, T (Dec 15, 2012). "". Lancet. 380 (9859): 2163–96. doi:10.1016/S0140-6736(12)61729-2. PMC 6350784. PMID 23245607.
    27. diabetes type 2 natural way eating plan (👍 guidelines) | diabetes type 2 natural way foods to avoidhow to diabetes type 2 natural way for ^ Snyder, MJ; Gibbs, LM; Lindsay, TJ (1 August 2016). "". American Family Physician. 94 (3): 227–34. PMID 27479625.

    Further reading[edit]

    • Bril, Vera; England, John D.; Franklin, Gary M.; Backonja, Miroslav; Cohen, Jeffrey A.; Del Toro, David R.; Feldman, Eva L.; Iverson, Donald J.; Perkins, Bruce; Russell, James W.; Zochodne, Douglas W. (June 2011). "". Muscle & Nerve. 43 (6): 910–917. doi:10.1002/mus.22092. hdl:2027.42/84412. PMID 21484835. Archived from the original on 2015-02-16. Retrieved for 1 last update 03 Aug 2020 2015-01-082015-01-08.
    • Pop-Busui, Rodica; Boulton, Andrew J.M.; Feldman, Eva L.; Bril, Vera; Freeman, Roy; Malik, Rayaz A.; Sosenko, Jay M.; Ziegler, Dan (20 December 2016). "". Diabetes Care. 40 (1): 136–154. doi:diabetes type 2 natural way glucose levels (⭐️ straight talk) | diabetes type 2 natural way unspecifiedhow to diabetes type 2 natural way for 10.2337/dc16-2042. PMID 27999003.

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